The first American department store, and home to the largest operating musical instrument in the world.

This charming colonial alleyway is one of the oldest continuously used residential streets in the U.S.

Dr Barnes' $25 billion private collection of art and arboretum.

This might just be the TARDIS of bookstores.

Eccentric concrete mansion and museum designed and built by hand from the inside out.

World's first "penitentiary," meant to be humane, drove men insane.

Fragments of architectural wonders from around the globe are embedded in the newspaper building's walls.

This small museum gives visitors a chance to soak up the history of the "sponge capital of the world."

An icon among Florida's pre-Disney tourist attractions.

The twin towers in this Chicago fountain use 50 foot tall video screens to spit on people.

This historic hotel invented the chocolate brownie.

One-time winter retreats of prolific inventor Thomas Edison and his friend Henry Ford.

This massive stained-glass masterpiece is thought to be the largest Tiffany dome in existence.

An enormous park-like oasis, full of famous Chicagoans' graves.

Florida might be at its most surreal in this museum devoted to the famed Spanish artist.

A blend of art, antiquities, and Americana fill this museum, surrounded by whimsical, enchanting gardens.

Holding multiple historical boats and an entire 19th century village, this New England attraction is the largest maritime museum in the world.

The former home of Samuel Clemens and family remembers the happiest period of the author's life.

Quirky castle designed by the American actor best known for portraying Sherlock Holmes on stage.

A historic freight system that found the true gold rush is in tourism.

This historic collection of Native Alaskan artifacts was resurrected through a partnership between the WPA and tribal artisans.

A rare chance to get up close and personal with a 13-mile ribbon of ice near downtown Juneau.

It may look like no more than a full-scale model, but every part of this full Space Shuttle stack had a working role in aviation history.

One person's lost luggage is another person's treasure.