A plaque on the side of a parking garage marks the burial place of a great Ottawa chief.

This tower commemorates the spot where George Washington hoisted the Grand Union flag.

The obelisk meant to mark the founding father's grave at Monticello is actually on the University of Missouri campus.

The iconic remains of the original Academic Hall that burned down in 1892.

Curious cave that stays a cool 56 degrees all year long.

This museum presents a dogged pursuit of 500 years of veterinary history.

This simple gravestone remembers a pig who single-hoofedly raised $19,000,000 for the Navy.

This former Union fort commands a fine view of downtown Cape Girardeau and the Mississippi River.

This 1854 courthouse along the Mississippi River has a storied history.

The maximum security facility was once thought to have "the bloodiest 47 acres in America."

A gem in the small Missouri town where Winston Churchill coined the term "Iron Curtain" and effectively began the Cold War.

Abraham Lincoln's likeness rests at the top of this giant totem pole.

The world's second largest rocking chair is found on Route 66 in Cuba... Missouri.

In the loving memory of a tragically deceased role-player this Illinois park is decked out with both dungeons and dragons.

Twice a year, this road is closed off to allow for the migration of thousands of snakes, reptiles and amphibians between cliffs and a swamp.

The famous Beatle secretly visited this Illinois town several times to visit his sister.

Nestled in Onondaga State Park, over 100 canoes carefully stacked in a replica of the famous standing stones.

This "little gallery in the middle of nowhere" is housed in a 170-year-old horse barn in the Missouri Ozarks.

A subterranean haunt where wine and homemade biscottis are always on the menu.

The hometown of Popeye's creator is littered with a growing collection of granite cartoon characters.

Now nearly abandoned, Kaskaskia was once the capital of Illinois and one of the most important towns on the upper Mississippi.

A museum dedicated to man's boldest venture.

The world's largest man-made underground caverns offer unparalleled underwater wonders.

Built in 1869, this now-retired structure looks more like a medieval fortress than a county lock-up.