A Wild West jailhouse that slid down the mountainside.

Dramatic river bend surrounds a natural red-rocked pedestal.

Ninety feet off the valley floor is an ancient dwelling put under protection of the U.S. government by Teddy Roosevelt.

An urban laboratory.

Come for the pizza, stay for a performance on the world's largest theater pipe organ.

Founded by members of the Tohono O’odham Nation, this one-room joint's James Beard–winning fry bread is light as a cloud.

A working cattle ranch with remarkably well-preserved prehistoric petroglyphs and ancient ruins.

Take a monster truck tour around an ostrich farm in the middle of the desert.

L. Frank Baum wrote part of the "Wizard of Oz" series in this wooden Victorian beach resort.

Semi-recognized center of the world, with many oddities.

Hidden on a cattle ranch in Arizona, this bookstore has been celebrating Southwest literature for more than 40 years.

A reproduction of earth's many biomes.

This southwestern historic site was designed and built by an artist who wanted his work to "feel at home."

A Tucson museum and performance space full of found-object movable sculptures.

This narrow coastline trail through the dense Kauai wilderness is among the most beautiful and dangerous in the world.

Brightly colored 30-foot-tall totems light up the desert sky just outside Las Vegas.

Nevada's largest cactus collection stands outside a candy mogul's small factory.

Decades' worth of lost and forgotten objects make up the collection of this tantalizingly odd little museum.

These banned cigarette vending machines now sell little pieces of pocket-sized art.

This Japanese treats shop may have been the first business to mass-produce fortune cookies in the United States.

An artsy hidden staircase leads to breathtaking views of San Francisco.

Experience a quartz crystal sound bath inside a storied, all-wood sound-chamber.

This unlicensed collection of fast-food memorabilia sits on the site of the first ever McDonald's restaurant.

These lush groves of fan palms rise up like oases out of southern California's Colorado Desert.