The first American department store, and home to the largest operating musical instrument in the world.

This palatial botanical garden is home to one of the largest pipe organs ever installed in a private residence, and a piece of Wood's cycad.

A stone arch leads to a cavernous 1930s spring house tucked away in the Pennsylvania woods.

America's most famous museum of medical oddities is home to the remains of Albert Einstein's brain.

World's first "penitentiary," meant to be humane, drove men insane.

This poor little statue is the most vandalized memorial in Washington.

Live data is transmitted from the Atlantic coast to instantly recreate the ocean waves in this fountain at the NOAA headquarters.

An intricately designed junk art house with four extravagant junk art cars hidden in the suburbs.

Baltimore's first skyscraper may be home to the inspiration behind pulp fiction's most celebrated bird.

This bug-eyed water wheel uses the power of the Sun to clean up Baltimore Harbor.

A set of rowhouses built for laborers at a glass company are the last of their kind in Annapolis.

The fifth-longest suspension bridge the world, connecting one Michigan peninsula to another.

The sci-fi villain is a little-known inhabitant of the U.S. capital's largest cathedral.

A rotating cast of guys and dolls in front of a Washington, D.C. building.

This missionary's legacy looms large over the Upper Peninsula of Michigan—literally.

As its grandiose name implies, this wooden dome is unsurpassed in size.

Island where motor vehicles are banned -- home to the only carless highway in the United States.

Strange physical sensations and optical contradictions keep visitors coming back for more.

"The Most Boring Road in the State."

To truly appreciate Detroit's landmark skyscraper, you have to step inside.

These enduring murals depicting a distinctly Marxist tribute to capitalism could not even be defeated by McCarthyism.

A sealed test tube said to hold Thomas Edison's dying breath was given to the inventor's friend and mentee, Henry Ford.

The only surviving prototype for Buckminster Fuller's house of the future.

One of the few working locomotive roundhouses in the United States.