A sign at the end of the Santa Monica Pier marks the traditional end of the legendary American highway.

Ninety feet off the valley floor is an ancient dwelling put under protection of the U.S. government by Teddy Roosevelt.

Not merely a museum – but a whirring powerhouse that offers a subterranean peek into the heart and soul of cable car operations.

A spiritual vortex among the red rocks in Sedona.

The granddaddy of all tourist traps, built on ice water, jackalopes, and a giant dinosaur.

Frank Lloyd Wright's most iconic home dangles over a Pennsylvania waterfall.

A island reachable by a causeway at low tide is possibly one of the earliest Western European locations to be identified in text.

Quite simply the largest tree in the world (by volume).

See massive fossils that are over 200 million years old in northeastern Arizona.

A Saint Nicholas-themed ghost town in the Mojave desert.

This former tuberculosis research hospital endeavored to cure the dreaded disease with fresh air and positive attitudes.

The sci-fi villain is a little-known inhabitant of the U.S. capital's largest cathedral.

A pedestrian island in the middle of world-famous Times Square emits a strange (and purposeful) humming noise.

The trials and tribulations of marking Poe's grave.

The popularity of Sherlock Holmes led to the creation of his fictional address, turning the orderly London street numbers askew.

One part local history, 99 parts gruesome haunted house.

The gorgeous library at Trinity College is home to remarkable treasures of Irish identity.

Explore the largest pure gypsum deposit in the world, and go dune sledding while you're at it.

A beautiful geyser under environmental threat.

One of the tallest buildings in Iceland, and perhaps, the most visually impressive.

This 4,000-foot-diameter hole is touted as "the most well known, best preserved meteorite crater on Earth."

The first declared National Monument in the United States.

Famously misunderstood wonder of the ancient world

Try not to get slimed in Tribeca.