This unmarked and unloved Manhattan subway grate created one of the most iconic images in American cinema.

The name of this famed hospital was once a byword for the horrors of medical and psychiatric care.

The oldest operating apothecary in the US has treated everyone from Thomas Edison to Mark Twain.

These historic buildings once housed the headquarters of one of the most infamous gangs of New York.

This hidden library of physiological ephemera contains centuries worth of knowledge on the vim and viscera of the human body.

The last remnants of what was once one of the world's grandest hotels can now be found in a Manhattan subway station.

The only remaining building in New York to see the inauguration of a president is being slowly overtaken by a grocery store.

A staggering collection of photographs depicting medical, social, and historical change.