This slender three-story building has also had several famous residents.

The oldest operating apothecary in the US has treated everyone from Thomas Edison to Mark Twain.

An aptly-named street near the birthplace of the modern LGBT rights movement.

New York City's smallest piece of private property.

A tiny museum housed in a New York freight elevator specializes in the "overlooked, dismissed, or ignored."

Try not to get slimed in Tribeca.

La Monte Young and Marian Zazeela's "Dream House" will immerse you in an ever changing world of sound and light.

The world’s oldest and biggest bookstore stocking only mystery, crime fiction, espionage, and thrillers.

This sculpture by artist Fritz Keonig survived the 9/11 attacks and now stands as a monument to the victims.

The last living thing to come out of the rubble after 9/11 is now a symbol of hope and resilience.

An artist's cute bronze subway sculptures belie his violent artistic past.

There must be a pun in this haystack somewhere...

The iconic Manhattan corner that was once the site of the Beastie Boys' fake clothing store.

A discreet little stairway on St. Nicholas Avenue leads to a quaint and unexpected cobblestone street of 19th century wooden rowhouses.

Avoid gangster interaction while window-shopping.

An uber-secure, windowless tower of doom in the center of Manhattan is an NSA spyscraper.

This mosaic dedicated to John Lennon was tended for years by a Beatles super-fan.

For over 30 years the walls of this Harlem schoolyard have been a gallery of street art by "Kings and better."

Behind a bodega is a small museum of relics and ephemera showcasing the history of New York.

A pedestrian island in the middle of world-famous Times Square emits a strange (and purposeful) humming noise.

Tucked in a nondescript downtown Brooklyn mall is a bar containing a remarkable turn of the century anatomical wax collection last seen in 1920s Berlin.

The oldest surviving bridge in New York City, which reopened to pedestrians in 2015.

This unmarked and unloved Manhattan subway grate created one of the most iconic images in American cinema.

A very classy 1920s-era bar right in Grand Central Station.