An extensive collection of reliquaries containing the bones of saints housed in the largest Catholic church in Venice.

A new sculpture calls attention to climate change in the centuries-old city it threatens.

100 year tradition of fist fights, marked by marble footsteps.

The plague quarantine island home to the alleged "Vampire of Venice."

Go inside to really appreciate this 500-year-old technological masterpiece.

Venice's "Island of the Mad."

This community on a small Venetian island has taken to painting their houses in bright neon hues.

In Florence's great Duomo, a 26 foot fresco honors a mercenary famous for attacking Florence.

This private skyway is filled with art and was expanded explicitly so that Hitler could appreciate a river.

Renaissance hospital featuring a rotating door into which unwanted babies were dropped.

A large grotto built in the 16th century amidst Florence's famous Boboli gardens.

One of Catholicism's four major basilicas has a series of papal portraits that are said to predict the end of the world.

Stone memorial that's said to predict the death of the pope and the site of the Cadaver Synod.

A sculpture serving as an homage to Pope John Paul II.

If you want to talk to the Pope you will have to stare down this surreal vision of Jesus rising from a nuclear hell.

More sculpture than building, this architecturally significant temple was built on the spot of Saint Peter's crucifixion.

This ritzy Italian market is built around a statue of an unforgiven heretic who was burned for his belief in an endless universe.

2300-year-old Roman road connecting the empire.

The yawning maw of this pagan visage is said to bite off the hands of liars.

The only "Egyptian" pyramid in Europe and the legendary tomb of Remus.

A master of trompe-l'oeil creates a stunning, tourist-fooling dome out of a flat ceiling.

A small island less than half a mile from Venice is a forbidden island with a dark and twisted past.