The small peaceful island off the Venice tourist circuit is where the city began more than 1,500 years ago.

Originally a leper colony, the island is now an Armenian monastery that's home to an incredible manuscript library and eclectic museum.

An extensive collection of reliquaries containing the bones of saints housed in the largest Catholic church in Venice.

The marble facade hides a little-known medical museum with early surgical instruments and rare copies of canonical texts.

Venice's "Island of the Mad."

Worm salt and other local ingredients are on the menu at this cult favorite ice cream shop.

CDMX's home for the world's culinary delights.

By night, this auto repair shop turns into a taquería serving up some of the city's finest al pastor tacos.

The famous artist couple lived and worked here, in two different houses separated by a bridge.

66,000 pieces of art, donated by one of the world's richest men.

Frida Kahlo's childhood home, now a museum of her life and works.

Underneath downtown Lincoln resides a network of caves that was also the city's first brewery.

This historic cliffside mansion uses a natural cave for air conditioning.

The history of the treatment of mental illness, illustrated in all its gory detail, and housed in an asylum.

These otherworldly limestone formations jut out from the Kansas prairie.

Journey up the capitol building's cupola for an amazing view of Topeka.

A vision of beautiful Hindu architecture in the middle of the American South.

This set of rickety spaceships are prepared to give alien travelers a place to relax and go to the bathroom.

I-95's Tijuana-style celebration of kitsch at the Carolina border.

One man's extraordinary topiary garden in a small South Carolina town.

A curious blend of taxidermy, antique tools, creationism, and a purported antediluvian rock.

Joe Minter is only doing the work of God in his yard, he says.

The uniquely-designed winter home and sculpture studio of Anna and Archer Huntington.

Oldest unrestored plantation house in America that is open to the public.