Itinerary Sponsored by Graduate Hotels

Study Guide: Road Trip from Knoxville to Nashville

East Tennessee boasts some of the state’s most beautiful highways and byways. Rather than rushing from one destination to the next, this is the perfect road trip to meander and stop along the way. Follow this suggested itinerary between Knoxville and Nashville, and you’ll discover lesser-known historical gems, stunning natural landscapes, and some memorable treats, all bookended by two of Tennessee’s truly great cities.