These beautiful wineries were at the center of Lake Erie's "grape belt" back when the Midwest dominated American wine production.

A giant lumpy candle serves as a beacon for this highly scented pit stop.

Knoxville’s architectural icon was the symbol of the 1982 World’s Fair, even catching the googly eye of Bart Simpson.

The iconic remains of the original Academic Hall that burned down in 1892.

The Old Courthouse takes visitors on a captivating trip through St. Louis' timeline.

The "World's Largest Underground Business Complex," a 55,000,000-square-foot city underneath Missouri.

After a water tower painting was accused of being an ad, a simple fix was made that gave the city a motto.

This steamer is known as "The ship that built Cleveland."

A favorite of Amelia Earhart, ranking among those rare bridges that can be crossed without changing sides of the river.

An office built to look like a giant basket.

The heroic sled dog of the 1925 serum run is preserved in taxidermy.

Cleveland's giant "free" stamp is a nod to the Civil War, but was misinterpreted for years.

Funded by John D. Rockefeller, this is one of the earliest, and most beautiful, shopping arcades in America.

The highest point in Tennessee, Clingmans Dome bears witness to the ravages of one type of insect.

A recreation of the doomed ocean liner in the middle of the Smoky Mountains.

An unusual, super-sized grocery adventure awaits in an Ohio suburb.

A bronze of the man in all his sinewy glory celebrates his longtime connection to the Ohio city.

An eccentric park and pool.

Once called the "Polish Gold Coast" it is an icon of the neighborhood that bears its same name.

To find the "unicorns of the deep" you've got to go downstairs.

The twin towers in this Chicago fountain use 50 foot tall video screens to spit on people.

An abandoned asylum incorporated into a college campus.

The largest clock face in the United States is twice the size of Big Ben and infinitely more ad-sponsored.

A giant ball made from pieces of an old Jeep.