The birthplace of Appalachia's only first lady, who some have dubbed the United States' "first female president."

Knoxville’s architectural icon was the symbol of the 1982 World’s Fair, even catching the googly eye of Bart Simpson.

Abandoned for 60 years, this submerged bridge was completely forgotten until the lake was drained.

This winding road of 318 curves is a must-visit for (careful) motorcycle and sports car enthusiasts.

Mile-long cave system near Great Smoky Mountains.

For two weeks every June, fireflies in the Smoky Mountains perform an astonishing light show.

An abandoned town is hidden in Great Smoky Mountains National Park.

The world's largest fire hydrant is supposedly tornado-proof.

A museum and doll store featuring a surreal and super sanitized version of where babies come from.

The record holder for the world’s largest peach.

Amazing pre-Civil War ruins alongside a shallow, rocky river that hosts beautiful (but endangered) lilies.

These strange large stones served as a campsite and lookout post for generations of Native Americans.

This Transylvania County city is home to a rare white squirrel population that is descended from an escaped carnival animal.

The U.S. Supreme Court's secret Cold War relocation facility in the mountains of North Carolina.

This nine-story building can be played like an instrument.

The highest point in Tennessee, Clingmans Dome bears witness to the ravages of one type of insect.