This former tuberculosis research hospital endeavored to cure the dreaded disease with fresh air and positive attitudes.

The highest point in Tennessee, Clingmans Dome bears witness to the ravages of one type of insect.

Better known as the "Body Farm," this unique research facility has been studying how human bodies break down since the 1980s.

Knoxville’s architectural icon was the symbol of the 1982 World’s Fair, even catching the googly eye of Bart Simpson.

One of corporate America's best-kept secrets is also one of the most publicly displayed.

The iconic Manhattan corner that was once the site of the Beastie Boys' fake clothing store.

This sculpture by artist Fritz Keonig survived the 9/11 attacks and now stands as a monument to the victims.

Yo, Adrian!

America's most famous museum of medical oddities is home to the remains of Albert Einstein's brain.

A sealed test tube said to hold Thomas Edison's dying breath was given to the inventor's friend and mentee, Henry Ford.

The 80-foot tire that looms over Michigan's I-94 was once a Ferris wheel in the New York World Fair.

Berry Gordy Jr.'s old home was the original headquarters of Motown Record Corporation.

Controversial tribute to the heavyweight champion boxer who grew up in Detroit.

This public baseball field is a beloved remainder from of one of the most historic stadiums in the country.

This downtown Dallas art installation is always on the lookout.

A symbol of Texas pride.

A house turned museum is the real-life "home" of the fictional main character of The Wizard of Oz.

This zombie-themed restaurant stands out in the heart of corn country.

Ever wanted to can Spam?

The cliff and rock formations are made out of Sioux Quartzite.

A fitting attraction for the corn capital of the world.

This old residential building was once the largest flour mill in the world.

When flour explodes, it's not a pretty sight.

After the musical legend's death, his memorial was mysteriously graffitied in gold.