Dedicated to the history of the health sciences.

An old train trestle re-imagined as an Egyptian obelisk.

The uniquely-designed winter home and sculpture studio of Anna and Archer Huntington.

This small museum dedicated to the painful memory of segregation is essentially a time capsule.

The sole remaining outpost of a once-thriving South Carolina chain still sells “pic-a-nic” baskets.

On Hilton Head Island this bronze King of the Sea rules all things briny—and lets you know if you’re late for lunch.

The only working large-scale tea plantation in the United States.

This natural wonderland is a unique chance to explore a Carolina bay, a mysterious geological formation of unknown origin.

This recently rediscovered Civil War-era submarine was the first to ever sink an enemy ship.

According to local lore, this narrow passageway through two large rocks was accidentally created by the devil himself.

A hobby born from insomnia has turned into a hangar full of objects that have been be-buttoned by the Button King.

Paths are maintained, but trees have taken over plots.

A rapidly disappearing authentic bit of the old south.

Granite outcropping that the state's tourism bureau doesn't promote because of its delicate ecosystem.

A quirky Poe-themed joint on an island keen to celebrate its overlooked connection to the famous writer.

4,000 monkeys used for medical testing on an island off of South Carolina.

Charleston's historic city jail once held everyone from pirates to Civil War POWs.

This natural spring not only claims to heal the wounded but it has also been willed to God.

Amazing pre-Civil War ruins alongside a shallow, rocky river that hosts beautiful (but endangered) lilies.

Oldest unrestored plantation house in America that is open to the public.

An unfinished rail tunnel that has since been used to house cheese and bats.

The oldest bridge in South Carolina may have been designed by the same man who created the Washington Monument.

"Not too many people can say they've had a nuclear bomb dropped on them, not too many would want to." — Walter Gregg.

South Carolina's last remaining slavery auction house is now a museum devoted to its own tragic history.