Once the last route taken by condemned prisoners.

An homage to Jackie Gleason's bus-driving character from 'The Honeymooners.'

An unassuming store hides relics of its former life as the jazz club that hosted some of the best black performers of the 1920s and '30s.

Pizza with a side of fine art.

Over 1,000 pieces of one of the most niche art objects imaginable: the glass paperweight.

Small and slightly hidden, the American Writers Museum is preserving the legacy of America's finest authors.

Home to a protest movement, a bombing, and a dramatic change in labor history.

Where Cusack's record store from the film "High Fidelity" was located.

An avant garde art museum at the University of Chicago.

In a quiet north Chicago neighborhood rests a stunning relic of the golden age of earthenware design.

The beloved home to all publications indie, erotic, and punky.

Prove you deserve to be fed by Kenny Shopsin.

A wonderful collection of all things Oz is nestled in the heart of Kansas.

The former home of Samuel Clemens and family remembers the happiest period of the author's life.

The city is full of whimsical portals to another world.

A house of courtship where the Jazz Age's most storied lovers got their start.

Dr Barnes' $25 billion private collection of art and arboretum.

While many places make the claim, the Library of Congress says this restaurant is the birthplace of the hamburger.

“Invented in Key West, Perfected in Brooklyn."

An impressive collection is dedicated to the legendary beast.

Radical Bookstore and Community Space.

Tracks near this Texas nature site were once thought to support the Creationist belief that man and dino coexisted.

A museum dedicated to the quirky and colorful world created by Springfield's favorite son.

Chicago's museum dedicated to the history of bondage and fetishism is more textbook than titillation.