The oldest operating pharmacy in the world features 800-year-old recipes.

The doodles of a genius line the walls of a secret room under the Medici Chapel, where they were hidden for nearly 500 years.

The middle finger of modernity.

This community on a small Venetian island has taken to painting their houses in bright neon hues.

This Venice bookstore has resigned itself to constant flooding by keeping its books in bathtubs and boats.

A 16th-century horror show built in a lovely Italian garden.

An idyllic mineral hot springs facility with a more-than checkered past.

The remains of the iconic train crash from the movie The Fugitive can still be found rusting along the Great Smoky Railroad.

An impressive collection is dedicated to the legendary beast.

A 17th-century bezoar, dirt from an infamous site, and other curios decorate this unusual bar.

A man's home is his castle.

In Florida, these naughty monkeys live on their own mini-monkey Alcatraz.

A sprawling maze of used books piled from floor to ceiling.

This set of rickety spaceships are prepared to give alien travelers a place to relax and go to the bathroom.

Renaissance villa and gardens complete with a tormented colossus.

After World War II, this former concentration camp in Northern Italy became a refuge for those displaced by the war.

One of the most well-preserved castles in Italy also contains a rare medieval example of a port fortification.

Massive galleon from a box-office bomb docked in Genoa.

A slightly creepy gallery of plaster cast models in the same museum as Michelangelo's David.

Venice's "Island of the Mad."

Those who own or stay at this 500-year-old, allegedly cursed house often meet terrible fates.

This ever-changing arrangement of naked dolls even caught the attention of "The Walking Dead" crew.

A traditional American farmhouse plopped in the middle of a Piccadilly courtyard.

Drink your espresso at a Victorian-era urinal in this underground-restroom-turned-coffee-bar.