This former textile mill was the last working cotton mill in Clitheroe, Lancashire. It was steam-driven until 1973. Since its redevelopment as a brewery, hospitality, and retail complex, much of the steam infrastructure has been retained.

The old steam engine has pride of place in the room known as the Engine Room, but perhaps the greatest current claim to fame is the bar in the German-style Beer Hall. It claims to be home to the longest bar in the United Kingdom. There is also a cinema, a hotel with 39 bedrooms, and a food hall.

Holmes Mill grew over the 19th and 20th-centuries. The first steam engines were beam engines (at least two were operating together at one time) were replaced in 1910 by a horizontal compound engine, which was used until the mill closed in the 1970s.

The redevelopment of the closed mill took place from 2015 onwards and the site is regularly used for special events The brewery produces a wide range of craft beers and brewery tours are available.