This home is decked out like a psychedelic explosion of colors and bowling balls.

One of Philadelphia's largest murals resides hidden under this bridge.

Erected in 1697 this Philadelphia bridge is the oldest surviving roadway bridge and perhaps the oldest stone bridge in the United States.

South Philadelphia is home to Keith Haring's only surviving in situ collaborative public mural.

Instruments, apparatus, and rare books all relating to chemistry and its related sciences.

Ant sculptures march up the side of what used to be an iconic spot in punk rock lore.

In the early 1800s, surgery was also a show.

One artist's love letter to his city and its citizens plays out across dozens of bright murals painted on the sides of decrepit buildings.

The oldest surviving botanic garden in the United States.

This charming colonial alleyway is one of the oldest continuously used residential streets in the U.S.

Mural made of 100,000 pieces of hand blown glass, and until recently, the largest glass mural in the US.

America's most famous museum of medical oddities is home to the remains of Albert Einstein's brain.

A rare view of a preserved Victorian science museum.

A layered tribute to the work of mosaicist Isaiah Zagar.

Ruins of a historic medical facility sits eerily by the water.

The sea urchin sculpture is an unusual commemoration of a New England town's seafaring history.

Once a kitschy symbol for a gift shop, this 38-foot seahorse is now a staple roadside attraction.