More than 450 years ago, an Italian nun became the first woman to paint the iconic subject.

Some say this medieval church is where the poet Dante married his wife and also met the love of his life.

A medieval weapon rumored to have been used by the brilliant poet himself.

This strange bovine gargoyle is said to have been put in as a passive aggressive form of revenge.

The mummified relic of St. Antoninus.

Secret refuge and museum of the Duke of Florence.

This private skyway is filled with art and was expanded explicitly so that Hitler could appreciate a river.

A large grotto built in the 16th century amidst Florence's famous Boboli gardens.

The doodles of a genius line the walls of a secret room under the Medici Chapel, where they were hidden for nearly 500 years.

The oldest operating pharmacy in the world features 800-year-old recipes.

The middle finger of modernity.

The engineering wonder and pleasure dome of a much-maligned emperor still holds undiscovered secrets.

The only "Egyptian" pyramid in Europe and the legendary tomb of Remus.

Rome's semi-secret peephole vista is also a former Crusader stronghold.

The yawning maw of this pagan visage is said to bite off the hands of liars.

A master of trompe-l'oeil creates a stunning, tourist-fooling dome out of a flat ceiling.

Architectureal fantasy quarter of Rome.

Hundreds of lucky felines haunt the ruins where Caesar was murdered.

The crypts of Capuchin friars decorated with the bones of over 4,000 friars, including an entire "crypt of pelvises."

Fantastically decorated underground chambers built in the 1760s.

A 4,000-year-old burial site hides behind a roadside Burger King.

The smallest pub in Britain was once a cabinet of curiosities and it still has the dead cat to prove it.

This historic franken-chapel is the oldest wooden church in the world, at least part of it.

The biggest and deepest Cold War bunker open to the public can be found in southeast England.