The seat of Buffalo government is a gorgeous Art Deco palace.

A museum dedicated to exhibiting remarkable outsider art.

The last of Philadelphia's wood-paved streets is now a landmark of terrible engineering.

A legendary boxing venue and ring featured in Rocky V.

Golden and naked, the figure that was once the highest point in New York is all that remains of the second Madison Square Garden.

A tour de force of a fountain, memorializing a man who loved fountains more than anything else.

A daily replay of the experiment that proved the rotation of the Earth.

This elaborate towering structure was once famed for its revolutionary height.

Ant sculptures march up the side of what used to be an iconic spot in punk rock lore.

Yo, Adrian!

The first American department store, and home to the largest operating musical instrument in the world.

Dr Barnes' $25 billion private collection of art and arboretum.

America's most famous museum of medical oddities is home to the remains of Albert Einstein's brain.

Pink, packed sanctuary and home of the world's fullest-time Elvis fanatic.

This university research project is the U.S. government's weed dealer.

William Faulkner kept his beloved estate wild and untamed.

The oldest family-run restaurant in the United States is a living museum of New Orleans dining history.

The oldest cemetery in New Orleans, resting peacefully for over 200 years now.

Walk the whole Mississippi River!