The oldest operating apothecary in the US has treated everyone from Thomas Edison to Mark Twain.

A celebration of capitalism in Midtown.

This unmarked and unloved Manhattan subway grate created one of the most iconic images in American cinema.

Mysterious 500-year-old tapestries depict a unicorn hunt.

Hidden in an ordinary Midtown building is a one-room museum dedicated to the greatest escape artist.

Become a prohibition rebel.

Hidden in Central Park's Ramble is a troublesome cave buried just beneath the surface.

One of only two commuter aerial tramways in the United States.

New York City's smallest piece of private property.

Whisper secrets in a busy station only to be heard on the other side of this acoustic arch.

This little museum is built on a theater that was once a wildly elaborate speakeasy.

The one-stop shop for all of your superhero (or evil arch-nemesis) needs.

A New York garbage depot holds a secret collection of weird and wonderful refuse.

Order scoops of pandan, lychee, and black sesame at this family-run institution.

The world’s oldest and biggest bookstore stocking only mystery, crime fiction, espionage, and thrillers.

A miniature rainforest is growing inside of a Midtown Manhattan office building.

The oldest family-run luncheonette in New York, last renovated in 1948, still serves food and drinks the old-fashioned way.

Try not to get slimed in Tribeca.

Dodge prohibitionists and slide through the telephone booth in Crif Dogs.

A treasure trove of artifacts, books, and artwork from the "golden age" of exploration.

A crumbling hospital from the 1850s on Roosevelt Island.

Townhouse facade doubles as an RMS Titanic Memorial.

A veritable variety of odds and ends.

Walk over a 150 year old manhole.