This sprawling collection of saintly relics includes such fascinations as wood from the Cross of Jesus and threads from Mary's veil.

One of Frank Lloyd Wright's greatest—and favorite—architectural masterpieces was almost lost.

A beautifully designed asylum was resurrected as a hotel and art center with a ghost story or two.

The absurd creation is a compulsory destination for selfies in Buffalo.

A bar, burger joint, and arcade housed in a late 19th-century church building.

Rochester's signature culinary delicacy.

The floor-to-ceiling collection in an old factory is a unique alternative to stuffy galleries.

The home, museum, and death site of Kodak's influential founder.

This natural rock "church" might not be a proper chapel but that doesn't mean it's not beautiful.

Why have you never heard of the second most popular tourist site in New York?

This sandstone gorge in New York State's Adirondack Mountains is home to waterfalls, flumes, and more.

The world's largest kaleidoscope, designed by a 1960s psychedelic artist.

Discovered by cows, these upstate New York show caves are presented with a healthy dose of psychedelic folk art.

An overlooked monument to the celebrity gangster who helped put the sin in Sin City.

A blacklight mini-golf fever dream pays tribute to the iconic rock band.

Unusual house, in an unusual neighborhood, home to some very unusual peanuts.

One part antique store, one part curiosities hodge-podge.

An abandoned water sports stadium that has become a haven for graffiti and decay.

This historic iron-working village is now a ghost town so immaculate that it looks as though it was recently built.

A gardener's enduring labor of love is spread throughout a small Vermont town.

Cheap art and political theater in Vermont.

A classic roadside attraction on Vermont's historic Route 5.

Taxonomy experiment known for quirky collections.

This "common-as-dirt" museum celebrates the glory of normalcy.