Tucked away atop a quaint Alabama pharmacy is this tiny display of antique medical tools.

The only cave in Louisiana has played host to a state's-worth of clandestine activities.

This ancient settlement contains some of the largest earthen mounds in North America.

Medical museum featuring a number of excellent medical models.

The oldest active juke joint in the state sustains a niche school of blues guitar.

“The Cajun Music Capital of the World” has kept things French in a Louisiana prairie town for over 75 years.

A museum within a former train depot tells the true story of a distinctly French-Louisiana musical genre.

The only place to see live frogs don pigtails and top hats, then eat their scrumptious legs.

A blues musician so talented that people said he must have traded his soul to the devil was born in this house.

A 200-year-old bar is all that remains of one Mississippi River town's rough-and-tumble past.

The second-largest ceremonial mound in the United States is an artificial hill that is loosely shaped like a pentagon.

One of the few existing, fully functional Showbiz Pizza animatronic shows.

This 19th-century benevolent society and jazz hall was rescued from abandonment to again host live music.

A parade of interactive nostalgia nestled within a giant brick building in downtown Hattiesburg.

A cheeky alleyway window hosts tiny rotating exhibits with outsized charm.

This largely forgotten piece of Cold War history stands hidden in the woods just north of the Mississippi Gulf Coast.

This Louisiana folk art gallery is a gnarled collection of driftwood homonculi.

A mysterious find dredged from Louisiana waters.

This sculpture may be the only known depiction of a man who helped finance the American Revolution and inadvertently created the dollar sign.

Religion and personal struggle gave birth to this collection of concrete angels.

This museum chronicles the history of a leprosy quarantine hospital that then became a refuge.

World's largest precision optical instrument used to detect Einstein's elusive gravity waves.

The stone labyrinth in this New Orleans city park was laid to symbolize healing in the wake of Hurricane Katrina.

Tiny historical streetcars wind through a small scale version of Crescent City in this whimsical train garden.