Colorful, cheeky signs spill out of legendary New Orleans folk artist Dr. Bob's Bywater studio warning you to "Be Nice—Or Leave."

A 19th-century shrine covered with prosthetic body parts as votive offerings.

A prime example of New Orleans' unique architecture these early 20th century homes were built to look like steamboats.

This cathedral dedicated to Louis IX, sainted King of France, holds many secrets.

A museum and shop on Bourbon Street located in the former home of the second Voodoo Queen of New Orleans.

A treasure trove of rare and exquisitely detailed antiques

A 200-year-old building in the French Quarter that was to be Napoleon's home in the New World.

A collection of oddities including Dr. Kevorkian's suicide device, the Thanatron.

This New Orleans statue of a portly figure in a goofy hat pays homage to a classic of satirical literature.

After the oysters have been shucked, and the restaurant's been shuttered, the terrazzo sidewalk from the 1940s is all that remains.

This bar named after the world's first mixed cocktail was home to one of New Orleans' most notorious politicians.

A little piece of Paris in the sultry south of the U.S.

This museum chronicles the history of a leprosy quarantine hospital that then became a refuge.

A theme park that suffered massive flooding during Katrina was abandoned, and now proves irresistible to trespassing explorers.

A museum of unusual collections, mini-towns, and a half-dog, half-alligator.

This Art Deco airport was once deemed “the air hub of the Americas.”

Before becoming a public park, this spot was a shell midden, a fort, and an amusement park.

The first patented shaved-ice machine heralded a snowy wonderland of iced treats at a favorite New Orleans summer shack.

A private museum dedicated to preserving the heritage of Mardi Gras' most beloved underdog parades, open by appointment.

This historic New Orleans cemetery is the final resting place of members of the Independent Order of Odd Fellows.

An otherworldly musical haven in The Big Easy.

This float factory takes the mask off of Mardi Gras and lets visitors see where the magic happens.

This symbolic piece of New Orleans architecture is also home to a few ghastly stories.

The second oldest continuously operating bar in Louisiana.