Brain collection and database that narrows the gap between man and animal.

The rooster who crossed the road lives on forever in Takoma Park, Maryland.

Fascinating museum dedicated to the under-appreciated medical history of urology features some wince-inducing devices.

The 320-year-old tree that greeted General Lafayette and rerouted an interstate highway.

This beloved Baltimore spot features caged dolls, a giant Pez collection, and many, many mannequins.

This free, take-a-book shop seems like a trick but isn't.

Crammed into a Baltimore row house is an oddities shop that sells everything from skulls to dead insects.

Its diverse collection of computers and technology spans the ages.

Easter in Westminster may be the only time and place to behold Edgar Allen Poe made entirely of Marshmallow Peeps.

This collection of odd proofs of concept is like taking a walk through the imagination of a Victorian engineer.

A blend of art, antiquities, and Americana fill this museum, surrounded by whimsical, enchanting gardens.

The first partially complete dinosaur skeleton was discovered here, forever changing the world's view of the ruling reptiles.

A giant light 13 feet high shines near Thomas Edison's old Menlo Park lab.

The first and only American institution dedicated to the enduring value of comedy in the United States.

Its original statue was deemed so ugly, locals called it “Scary Lucy.”

This two-room factory has been cranking out the musical signifier of zaniness for a century.

The absurd creation is a compulsory destination for selfies in Buffalo.

A forsaken wonder in the middle of the East Side neighborhood.

Western New York's largest independent bookstore doubles as a historical repository of all things Niagara Falls.

One of many reminders of Tesla's scientific contributions overlooks the falls which inspired him.

The birthplace of America's favorite fruit-flavored mystery dessert.

Called the “General Motors of the piano industry,” these buildings once produced as many as 700 pianos a week.

Eclectic architecture in the woods of New York.

Abandoned rock quarry now a haven for mountain bikers and hikers.