Colorful, cheeky signs spill out of legendary New Orleans folk artist Dr. Bob's Bywater studio warning you to "Be Nice—Or Leave."

A treasure trove of rare and exquisitely detailed antiques

The only rotating bar in New Orleans has been slowly spinning since 1949.

This New Orleans statue of a portly figure in a goofy hat pays homage to a classic of satirical literature.

This bar named after the world's first mixed cocktail was home to one of New Orleans' most notorious politicians.

This unique shop is full of memento mori art, antique medical equipment, secret society paraphernalia, and historical relics.

This historic "City of the Dead" lies prominently in the center of New Orleans' famous Garden District.

The first patented shaved-ice machine heralded a snowy wonderland of iced treats at a favorite New Orleans summer shack.

This knobby, drooping New Orleans oak is a favorite place both for climbing and for meeting giraffes.

La Monte Young and Marian Zazeela's "Dream House" will immerse you in an ever changing world of sound and light.

Giant works of art interspersed throughout meadows and woodlands offer a new discovery at every turn.

400 million-year old limestone caverns nestled in the Ozarks served as shelter and a hideout for cultures throughout North American history.

The world's second largest rocking chair is found on Route 66 in Cuba... Missouri.

A flat slab of stone perched hundreds of feet above the Gasconade River in the northern Ozark mountains.

The show pony of cave systems, Fantastic Caverns manages to live up to its name.

This museum features the original car used on the Beverly Hillbillies sitcom.

If there's another drive-through golf-cart bar in a bat-filled cave on top of a mountain, we don't know about it.

The warmest cave in the Ozarks features two seemingly bottomless lakes.

A short boardwalk through a swamp leads to the spot from which the Louisiana Purchase was surveyed.

A parade of interactive nostalgia nestled within a giant brick building in downtown Hattiesburg.

A cheeky alleyway window hosts tiny rotating exhibits with outsized charm.

This humble hole-in-the-wall is home to an incredible pig ear sandwich and serious civil rights history.

Built by prisoners of war, the largest small-scale model ever built includes eight miles of tiny streams that now sit abandoned.

The oldest active juke joint in the state sustains a niche school of blues guitar.