This meticulously extracted nervous system allegedly came from a 19th-century custodian who donated her body to science.

The oldest surviving botanic garden in the United States.

Philadelphia boasts one of the best — and most often overlooked — traditional Japanese gardens in North America.

This museum boasts a bucket of teeth and tells the tale of a 20th-century dental circus.

The humble field where the first Major League Baseball game was played.

A museum dedicated to the strange and extravagant costumes and memorabilia of the mummers, a tradition older than Philadelphia itself.

One of the oldest of its kind.

The tombstone of the founder of the lost town of Ogletown is now stuck inside a traffic median.

This colonial mansion has been home to a staggering number of American historic figures.

The headquarters of the Fraternitas Rosae Crucis, complete with Rosicrucian pyramids, all in the Pennsylvania woods.

This stone tower marks a lookout point over the historic Washington Crossing, and maybe some buried treasure.

A historic covered bridge is but one example of an oddly prevalent American urban legend.

A modern ghost town whose inhabitants were driven away by the growth of nuclear power.

This local gem houses the largest collection of pre-Raphaelite paintings outside of the U.K.

This weeping, 10-foot-tall sculpture was a maquette for a 9/11 memorial.

Mural made of 100,000 pieces of hand blown glass, and until recently, the largest glass mural in the US.

Instruments, apparatus, and rare books all relating to chemistry and its related sciences.

A toxic ghost town sitting atop a massive coal fire.

Eccentric concrete mansion and museum designed and built by hand from the inside out.

Mysterious rocks that ring musically when struck.

Outsider art meets paleontology at this roadside reptile repository.

Hellam Township is reputed to feature seven remote gates, which when passed through in the right order, open an entrance to hell.

Erected in 1697 this Philadelphia bridge is the oldest surviving roadway bridge and perhaps the oldest stone bridge in the United States.

The highest point in Delaware is located under a trailer so this marker across the street will have to do.