Home to the infamous "Typhoid Mary" and the worst loss of life in New York's history prior to September 11, 2001.

The feral felines of Roosevelt Island have a small army of allies and an abandoned hospital all to themselves.

The oldest family-run luncheonette in New York, last renovated in 1948, still serves food and drinks the old-fashioned way.

A crumbling hospital from the 1850s on Roosevelt Island.

A beautiful and abandoned New York subway station from 1904, complete with chandelier.

This former asylum for Black Americans is haunted by its history of violence and racism.

The haunting "Hell House Altar" is one of the few remnants of an abandoned college that has been a magnet for local legends.

Its diverse collection of computers and technology spans the ages.

This rare triple-jurisdiction drawbridge passes through Virginia, Maryland, and Washington, D.C.

Once part of a dam servicing an early 19th century grist mill, the tucked-way falls are a tricky-to-find urban oasis.

Historic home of America's sweetheart sharpshooter, Annie Oakley.

Remains of a historic fountain that was mysteriously lost in the demolition of a D.C. traffic circle.

A remarkable time capsule of American manufacturing deep in Maryland coal country.

Walk a trail through a historic Quaker town that outlawed slavery in 1777 and was a major waypoint on the Underground Railroad.

An eerie, decaying ghost town destined to fade into the forest.

This abandoned asylum was once a state of the art facility before devolving into one of the most deadly mental institutions in American history.

It's not hard to see why the historic Peabody Conservatory of Music's library has been described as a "cathedral of books."

The last of Philadelphia's wood-paved streets is now a landmark of terrible engineering.

This meticulously extracted nervous system allegedly came from a 19th-century custodian who donated her body to science.

This charming colonial alleyway is one of the oldest continuously used residential streets in the U.S.

World's first "penitentiary," meant to be humane, drove men insane.

A former mental hospital founded in the 1930s by a eugenicist who advocated for the forced sterilization of patients.

These unusual rooms on wheels are holdovers from the 1960s.

Standing for over 200 years, the abandoned home of a Revolutionary War hero and later a succession of prison superintendents.