The final resting place of the poets Shelley and Keats.

A large grotto built in the 16th century amidst Florence's famous Boboli gardens.

Venice's "Island of the Mad."

Sitting on an Italian hilltop is this surreal fortress built by the mad inventor of electrohomeopathy.

The skull of the patron saint of lovers lies in the Basilica di Santa Maria in Cosmedin—maybe.

The oldest operating pharmacy in the world features 800-year-old recipes.

2300-year-old Roman road connecting the empire.

According to the local folklore, the myriad colors of this lake are the result of a lovelorn wizard's blunder.

Stalactites and stalagmites in a beautifully lit cave.

The only "Egyptian" pyramid in Europe and the legendary tomb of Remus.

Pompeii's less famous neighbor is still revealing her secrets.

Renaissance villa and gardens complete with a tormented colossus.

Once known for its horse-powered knife sharpening, this 200-year-old shop offers an array of blades and hard-to-find culinary tools.

A popular legend claims that the famous pizza was invented at a restaurant in this alley.

Just across from the "Last Supper" painting is the famous painter's vineyard, a gift received for creating the masterpiece.

Get buzzed beholding one of the world's largest coffee-machine collections, then step into the café for a specially brewed cup.

This ancient walled garden turns fog into food.

A quiet Sicilian village is home to a cafe that had an important role in "The Godfather."

The middle finger of modernity.

The underground sanctuary of a mysterious ancient cult.

This hidden Art Nouveau courtyard is an opulent feast for the eyes.

A master of trompe-l'oeil creates a stunning, tourist-fooling dome out of a flat ceiling.

This community on a small Venetian island has taken to painting their houses in bright neon hues.

This Venice bookstore has resigned itself to constant flooding by keeping its books in bathtubs and boats.